Most person?s, who are certainly not globe-huge-internet internet marketers, do not entirely understand what web-site marketing is genuinely should be about. At its main, via the internet advertising is just a way to consider advantages of your huge features with the globe-huge-web to find considerably far more attainable purchasers. You will find a lot of information you really need to recognize after you get going website promoting and that?s where by state-of-the-art on the internet endorsing teaching can be purchased in.
Obviously, previous to you come to a decision to pressure about leading-edge on line marketing strategies you have to have to guarantee you use an organisation learn on the basic principles. With the numerous techniques for connecting with people on the net you have to understand the factors that do the job, and what correctly does not.
Another factor you may want to take into account may be the simple fact that factors over the internet modify promptly. What worked well excellent the other day, or throughout the past calendar year, often could not manage as adequately or they could possibly not manage at all.
A massive part with the cause for this is the lots of search engines like google are continually altering their programs (their techniques) while using assumed of boosting the ordeals of the on-collection consumers.
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Far more than one particular over the internet seller has upon the market to the day having an internet site that has been carrying out alternatively very well: located remarkably from the search engine rankings as adequately as obtaining an excellent option of targeted targeted visitors, merely to get up at sunrise to reveal that their when extremely standing site now on site 223 in the research outcomes.
Obviously you?ll find strategies to steer clear of may by far the most successful way should be to improve your website web page typically (primarily because on this, a great cope of via the internet online marketers benefit a Word media blog site type online web site. It?s straightforward to up-date) and give your earth-broad-net net-web-site attendees with many different excellent.
The important google have turn into greater at acquiring the capacity to discover excellent published subject material with a web page. They may reward that site by giving it a high placement around the look for consequences page.
Right here can be a small amount of of your via the internet marketing techniques tactics you can want to put into practice. A few of these is going to be considerably more about targeted traffic generation targeted at your internet site people are far more regarding transforming that prospects into paying out customers. However they are all very important:
1. Search Engine Marketing (Sem) ? if you would like your web-site scored really, you ought to let the serps understand what your website is around. Applying clear-cut Search engine ranking approaches with your web site can enable you obtain added absolutely free, targeted traffic.
2. Spend Each Click on Advertising (Advertisement) ? this superior technique of discovering site visitors can functionality speedily only while you find out how to make it work ideal. Additionally there is a learning bend and will amount to if you make mistakes.
3. Advertising and marketing with Mail: this definitely is additional about In .relationshipIn . with all your web site attendees and building trust with just about every besides in essence driving a car site visitors. On-line it can be not straightforward to differentiate yourself from everyone and enable people ?get acquainted with youIn or trust you. By finding a possibility to generate them e-mail by way of an interval it is actually manageable to produce partnership with these people.
Realizing some basic and leading-edge planet-huge-world wide web marketing ability can help anyone to switch your minor venture right into an extremely worthwhile practice. Even if informed traditional online business or maybe an ourite-the business sector internet site, mastering further knowledge can enable you generate more earnings.
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Researchers of the National Institutes of Health (NIH) looked at data from the Drug Induced Liver Injury Network, which evaluated patient information from eight sites across the US from 2003 to 2011.
Their findings disclosed that of 679 cases of liver injury, 93 (18 percent) were attributed to herbal or dietary supplements.
According to the results presented at the Digestive Disease Week meeting in San Diego, among patients who used supplements, 33 percent consumed bodybuilding products, 26 percent took weight loss goods, and the remaining 31 percent used a variety of other types of supplements.
?The number of cases in our network has increased over the years,? cautioned Dr. Jose Serrano of NIH. ?There were no deaths, but 7 percent of patients needed a liver transplant. These are not trivial consequences.?
About 40 percent of people in the US take herbal or dietary supplements. According to estimates, American consumers spent 26.7 billion dollars on supplements in 2009.
However, it seems that the people are less likely to be aware about those products? side effects such as hepatotoxicity or liver injuries.
Moreover, compared to medications, the highly marketed supplements are under much less strong regulation imposed by health authorities.
?There is so little regulation of the many products on the market,? said study leader Dr. Victor Navarro of Thomas Jefferson University in Philadelphia.
Experts suggest people to read the label?s of supplements carefully and consult with their physician before taking those products and do not assume that they are completely safe.
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Pre-market prices for Nasdaq stock, left, and Facebook stock are shown, Wednesday, May 23, 2012 at the Nasdaq MarketSite in New York. Facebook stock rose in early trading Wednesday, although still far below the $38 it was priced at before its initial public offering Friday. (AP Photo/Mark Lennihan)
Pre-market prices for Nasdaq stock, left, and Facebook stock are shown, Wednesday, May 23, 2012 at the Nasdaq MarketSite in New York. Facebook stock rose in early trading Wednesday, although still far below the $38 it was priced at before its initial public offering Friday. (AP Photo/Mark Lennihan)
The pre-market price for Facebook stock is shown, Wednesday, May 23, 2012 at the Nasdaq MarketSite in New York. Facebook stock rose in early trading Wednesday, although still far below the $38 it was priced at before its initial public offering Friday. (AP Photo/Mark Lennihan)
NEW YORK (AP) ? Almost four years after the financial crisis, Wall Street still can't get it right.
Investor anger mounted Wednesday over the initial public offering of Facebook stock last week, which was fumbled by the banks that managed the deal and complicated by technical problems at the Nasdaq stock exchange.
Shareholders filed at least two lawsuits against Facebook and Morgan Stanley, the bank that shepherded the IPO, over reports that it withheld negative analyst reports about Facebook from some clients before the company went public.
It was the second stumble this month by a major Wall Street firm. JPMorgan Chase, usually revered for taming risk, has yet to contain a growing $2 billion loss in one of its trading units.
The missteps are further eroding the confidence of Main Street, or what was left of it after the financial meltdown of 2008, and reinforcing the sense that the game is rigged.
Judson Gee, a financial adviser in Charlotte, N.C., placed a call Wednesday morning to a client who had plowed $50,000 into Facebook stock on Friday, the day of the IPO.
Gee said he called to tell the client, a restaurateur, about reports that Morgan Stanley had told only select customers about an analyst's reduction of revenue estimates for Facebook just before the IPO.
"I could see his jaw dropping on the other side," Gee said. "A lot of expletives came out." He said his client had asked: "How can they give that information to the big boys and not give it to the public?"
In the final planning of the IPO, Facebook, working with Morgan Stanley, raised the total number of shares being offered for sale by 25 percent, to 421 million. They expected extraordinary demand for the stock by investors.
That appears to have been a miscalculation. Facebook stock jumped from $38 to as high as $45 in the opening minutes, but quickly sank toward $38 again. It dropped to about $34 on Monday and $31 on Tuesday. The stock recovered somewhat on Wednesday and climbed $1.
Dayna Steele, a motivational speaker in Houston, said she planned to wait and buy the stock "when everybody finishes suing each other."
The shareholder lawsuit, filed in federal court in Manhattan, accuses Morgan Stanley of withholding the negative analyst report from some clients while it prepared to take the stock public.
One of the investors suing, Dennis Palkon, a professor at Florida Atlantic University, said that IPOs are tricky, but "this one had a lot of glamour, had a lot of interest. It has a lot of users. I thought it'd be a pretty good investment."
He bought 1,800 shares of Facebook at $38 through his ETrade account, meaning that after Tuesday, he was down more than $12,000 on paper.
"I think there were problems all over the place," he said. "It was totally poor planning to raise the price as high as they did and then to add all those extra shares."
Morgan Stanley declined comment on the suit, but it said on Tuesday that it had complied with regulations in how it handled analyst reports before the IPO. Facebook called the lawsuit "without merit."
The Senate Banking Committee, the Securities and Exchange Commission and other regulators also plan to look into the IPO.
Regulators will probably want to comb over Facebook's prospectus, the information it provided to potential investors, to make sure the company's disclosures were accurate and complete.
State securities laws and industry rules, mostly broader in scope than SEC rules, give state and industry regulators a wider berth to sanction investment firms that they accuse of failing to act in investors' best interest.
The first trading in Facebook stock, originally set for 11 a.m. Friday, was delayed half an hour by technical glitches at the Nasdaq Stock Market, and brokerages are still sorting through problems with orders.
A person familiar with the matter, speaking on condition of anonymity because the person was not authorized to speak publicly, told The Associated Press that Facebook was in talks with the New York Stock Exchange to move its stock listing there from Nasdaq.
The bungled IPO came little more than a week after JPMorgan CEO Jamie Dimon disclosed the $2 billion loss.
He has said the bank was hedging against financial risk, but regulators have questioned whether it was a gamble for profit instead, and have seized on the loss to make the case that Wall Street has not cleaned up its act.
Lisa Lindsley, director of capital strategies for the American Federation of State, County and Municipal Employees, which has 1.6 million members and handles pension assets of $850 million, said the union was "very concerned about the lack of internal controls at all three firms," referring to Facebook, JPMorgan and Morgan Stanley.
Elizabeth Warren, architect of the Consumer Financial Protection Bureau and a Democratic candidate for Senate from Massachusetts, said Wall Street has lost an image that once said, "We are solid and we will be here forever."
"Banking should be boring," she said, "because boring creates confidence."
As if small investors needed a reason to feel queasier, the stock market is having its worst month of the year, mostly because of concerns about a debt crisis in Europe and whether Greece will exit the euro currency group.
The Dow Jones industrial average gained 9 percent during the first four months of the year, but that has withered to 2 percent.
The Standard & Poor's 500 index more than doubled in the three years after its financial crisis low, in March 2009, and is still up 93 percent. But small investors, mistrustful of the market, are still pulling money out of stocks.
Investors withdrew $85 billion from U.S. stock mutual funds last year and have pulled more money out than they put in for five years in a row ? significant given how many Americans automatically put money in through 401(k) accounts.
They had already withdrawn $6 billion through April this year, and the decline in May figures to make the withdrawals accelerate.
To be sure, Main Street has a love-hate relationship with Wall Street. For the 1980s and 1990s, and for much of the 2000s, it tilted toward love, and bankers were hailed as masters of the universe.
When booms turn to bust, as after the crash of 1987, the bursting of the dot-com bubble in the early 2000s and crisis of 2008, the relationship quickly turns sour.
But for the institutions of Wall Street, these recent missteps could hardly come at a worse time. The presidential election is less than six months away, and the economy and the role of large financial institutions figure to play large roles.
When Congress passed an overhaul of financial laws in 2010, it was designed to prevent a repeat of the 2008 crisis. The details are still being written, and the financial services industry is fighting hard against many of those changes.
Two weeks ago, Treasury Secretary Timothy Geithner said the JPMorgan loss "helps make the case" for tougher rules for banks.
William Black, a former bank regulator who now teaches law and economics at the University of Missouri at Kansas City, said he believed the banks would still be able to water down the regulatory changes, even after these embarrassments.
The banks, he said, "are bringing a gun to a knife fight."
But the issues are not clear-cut. Michael Barr, a law professor at the University of Michigan who was an architect of the overhaul, said he was concerned that the Facebook episode might make it harder for other companies to raise money by taking themselves public.
"The more the system feels like it's rigged, the harder it is going to be for companies to raise money and for investors to freely participate," he said.
Ernie Patrikis, a former top official at the Federal Reserve's New York branch who is now partner in the banking regulatory practice at the law firm White & Case, said banks deserve part of the blame for spooking investors in 2008.
But he said regulators have been more rigorous since, some financial institutions have closed, and "a lot of CEOs went missing."
"I don't want to see a day of reckoning" for the banks, he said. "The banks are our lifeline."
___
AP Business Writer Marcy Gordon in Washington, AP Technology Writer Barbara Ortutay in New York and AP Radio correspondent Julie Walker in New York contributed to this report.
You?re not quite sure what happened when you turned your head for three seconds, but your toddler tossed something down the drain that has thrown a wrench in the entire home?s plumbing. One repairman quoted $50 and a quick fix, another $500 and a major overhaul.
Get a more concrete answer on Click and Improve, a new site that simplifies that process of getting work done. Based in Long Island City, the company works with a network of NYC-area home improvement pros who are on hand to solve any sticky situation. Start by typing in the service you need (paint a room, install an electrical outlet) and they?ll diagnose the issue, define the scope of the project, give an exact price quote and set you up with a (licensed, bonded, insured) local provider.
The con: You won?t get to hone your haggling skills. The pro: Hours of aggravation saved.
After the famous author Henry Miller visited Weeks Hall, master of The Shadows-on-the-Teche, he wrote that he had just been to ?that strange part of the world called New Iberia, Louisiana.? When I first moved there in 1964, I agreed with him. Rain fell throughout the month of January, and my first glimpse of Bayou Teche, a murky brown tributary, made me shudder. I thought I had arrived in a place where dark stained, well-soaked ground was the norm. I felt this way until spring came to Teche country, and I fell in love with a place that I now call ?unique,? rather than Miller?s word ?strange.?
During the lush spring, I learned to enjoy and appreciate the people of multicultural origins who had settled in the Teche country and formed a culture that fosters art, music, and writing. New Iberia is the place that nurtured world-famed author, James Lee Burke; the Blue Dog artist, George Rodrigue; the jazz trumpeter, Bunk Johnson; and many other notable artists who thrive in a warm, romantic culture.
In that multicultural atmosphere, I began to seriously write and continue to write poetry, living in New Iberia part of the year and deriving from the culture enough subject matter to fill more than thirty books. During my sojourn in New Iberia, I?m sometimes asked to speak to students interested in Creative Writing and to engage in two or three hour conversations with the aspiring authors in a room at the New Iberia Library where cultural events take place.
Five years ago, I was happy to discover that Susan Edmonds, who brought many outstanding programs to the library, had written and been awarded a grant to initiate a memoir writing class, aka the ?life writing class.? By the following year, the University of Louisiana at Lafayette had formed a similar class, and the two classes have been functioning since that time under the tutelage of Kim B. Graham of St. Martinville, Louisiana. Some of the students produce an essay or short story each week; others write poems or songs.?
All of the writing material is inspired by their personal lives and backgrounds. As Kim Graham says, ?Memoirs are written not so much to become famous, but to place value on a moment in time. This genre of writing is about how one remembers one?s life, or a part of one?s life, and not about the outcome of the life as a whole?we hear the writer?s voice and his or her style in each story??
This year, Kim engaged my friend Victoria Sullivan to publish the stories written by classes in New Iberia and Lafayette, and Let Me Tell You A Story emerged this month. It?s a book written by teachers, doctors, cowboys, housewives ? people who like to tell stories about family and about that unique part of the world known as Acadiana.
The book also contains photographs and drawings that capture the moment in time about which Kim spoke. Stories range from those that have been inspired by ancestry to humorous vignettes. At the risk of being chided for not including all of the writers in a review, I just wanted to share with readers of ?A Wordsworth,? a bit of humor from Glenn Oubre?s essay entitled ?Nicknames in My Home Town.? Glenn grew up in the small community of Loreauville, just down the road from New Iberia, and writes that Loreauville once had more nicknames for people than any small town in the U.S. ?Generally, the names were terms of endearment that made people feel good about themselves,? Glenn says. ?However, some names were mean and cruel and intended to ridicule. The names stuck like glue and stayed for a lifetime.??
The nicknames included important people like former Mayor Forbus Mestayer who was known as ?Bagasse,? which denotes sugar cane residue. This strange moniker was delivered in Cajun dialect. But most nicknames were more pronounceable ? ?Mutchie,? ?Te-boy,? ?Butsy,? ?Too Too,? ?Full Choke,? and ?Hesitation,? to name a few. Glenn even went so far as to prepare an alphabetical table featuring many of the names and to compose a poem (he is also a musician) of eleven quatrains; e.g., "There was Sue Sue, Cho Cho, and Goo Goo,/names that all sound the same./And Me Me, Ge Ge, and De De/they were their claim to fame?My neighbors in the country/were Poon, Too Loo, and Toe Joe./Next door were neighbors Te-Bic, and Ze Ze./Down the road lived Noo-noon and Low Low?? ?Pooyie, so much fun,? Glenn concluded his essay. And Pooyie, I agree!
Let Me Tell You A Story?will soon be available on www.createspace.com/3847239 and at Books Along the Teche bookstore in New Iberia, Louisiana. ?You're in for a reading treat when you sample these stories composed by authentic southern voices. A subsequent blog will highlight the Lafayette Life Writing Class?s publication, Wit, Wisdom, and Mostly True Stories.
If that you?re anxious which you are heading bald, you then commonly are not on your own in regards to this. This can be anything expert by lots of individuals sooner or later within their lives. It might be considered a intelligent factor if you should comprehended about why thinning hair happens. Though, only a doctor is skilled to clarify why that you?re heading bald.
The mission of this post should be to give attention to a number of the factors that may lead to thinning hair.
Pattern baldness can be a natural reason for thinning hair, however it just isn?t as frequent in females since it is in guys. Heredity can be a serious player in thinning hair. Each time your genes dictate that it is time for you to begin shedding your hair, which is when it?s going to get started ? it won?t make a difference what age you will be. Many people, as an illustration, might possibly begin dropping their hair while in the twenties or perhaps before. With pattern baldness, to start with you are likely to begin to view a receding hairline. A the vast majority of your respective thinning hair will take place about the best of your respective head. There is not an awful lot you could do concerning the genes you inherited, so that you will likely not meet a great deal good results dealing with your thinning hair with prescription drugs, health supplements, or herbs. Some fairly high priced remedies for all those that have pattern baldness are laser treatment plans or hair transplants.
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A tense practical experience can lead to thinning hair. That is generally real should the circumstances was tremendously traumatic or distressing. You most likely do not take care of emotional tension specifically exactly the same way as a second human being. In a few men and women it may possibly lead to bodily warning signs ? these as muscle mass pressure and thinning hair ? and even in medical-related complications. A person instance of thinning hair which will be blamed onto emotional tension occurs upon surgical treatment or some type of incident. When this occurs, but, the hair normally regrows. Whenever you are living by way of agonizing cases or are confronted by having an upsetting occasion with your lifestyle, it may possibly lead to emotional tension ? most likely sufficient to result in thinning hair. A person be aware to remember, nevertheless, is the fact that emotional tension would ordinarily need to be really acute and long-lasting for it to result in thinning hair. Nevertheless, it may possibly only be advantageous for your hair if you happen to make an energy to help keep the emotional tension degree with your lifestyle as small as you can.
Although folks don?t need to take it, but dropping hair is simply a reality of lifestyle. As you turned out to be a lot older, you hair will launch to skinny out. The greater you age, you will likely start to shed your hair. Sadly good enough, you could possibly realize that your hair arrives out more quickly than you can actually switch it obviously. One particular way which you could make this time inside your lifestyle significantly less nerve-racking is by obtaining hair transplants or putting on a toupee or wig. Regardless of how aged you may be, it?s best to talk to that has a medical doctor for those who launch dropping plenty of hair inside of a brief quantity of time. Certainly, your hair will launch to fall out when you mature older, but this could be in actions.
The factors major to some hair thinning is often obscure or quite simple. You stand an outstanding probability of getting your hair thinning reversed if it had been because of a health-related affliction that?s been efficiently handled or if you should have been not too long ago pregnant. For others, heredity can perform a large position in hair thinning and, if this is certainly your circumstances, you might have trouble selecting an answer. Unexplained hair thinning is often an issue as well as the most effective plan of action can be to head over to your health and fitness treatment specialized and understand the precise lead to.
VANCOUVER, British Columbia (AP) -Fredy Montero scored in the 90th minute to give the Seattle Sounders a 2-2 tie with the Vancouver Whitecaps on Saturday.
Eddie Johnson also scored for Seattle (7-2-2). Alain Rochat and Camilo scored for Vancouver (5-3-3) in front of a sellout crowd of 21,000 at B.C. Place Stadium.
Montero took Johnson's header on the run, lifted the ball around Vancouver captain Jay DeMerit, put it on the ground and fired home a shot from the top of the 18-yard box.
? 2012 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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Chelsea wins Champions thriller
Didier Drogba scored the decisive penalty in the shootout as Chelsea beat Bayern Munich to win the Champions League final after a dramatic 1-1 draw on Saturday.
The transport link between two Olympic venues that might not be ready for the Games. ITN's Simon Harris reports.
By Alastair Jamieson, msnbc.com
The world's most expensive cable car is undergoing tests in London ? but authorities admit the project, which links two Olympic venues, may not open in time for this summer's Games.
The 1,000-yard gondola lift line crosses the River Thames in east London and is planned to be both a commuter route and a tourist attraction.
It has been enthusiastically backed by London Mayor Boris Johnson, but opponents point out the scheme will use public money despite a huge $57 million?sponsorship deal with Dubai-based Emirates Airlines which means the facility will be officially known as the Emirates Air Line.
PhotoBlog: London's new Thames cable car in place - but will it be ready for the Olympics?
It will cost up to $95 million in total, with around $20 million coming from local public funds.
Transit authority Transport for London (TfL), which will operate the cable car, will only say the project will be open "in the summer," raising the prospect that it will not be ready in time for the London 2012 Games in July. TfL insists the route was never part of the Olympic transport plan.
Two 300ft-high pillars will carry more than 30 gondolas across the river from the O2 ? the Greenwich concert venue that will host events including the gymnastics and basketball finals ? to the Docklands-based ExCel conference center which is being used for boxing, fencing, judo, taekwondo, table tennis, weightlifting and wrestling.
The cost of a journey on the Emirates Air Line has not yet been set, but TfL says it will be similar to the frequent Thames River Boat service whose fares are around $8. Passengers will be able to pay with Oyster cards, the pre-payment "smart card" used?by millions of Londoners.
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A diverse community in East London will welcome the world to Britain for the 2012 Olympic Games. Meet residents and hear how they feel about having a huge, world stage in their backyard.
Although the cost will be significantly higher than the equivalent bus or subway journey, the views from the 10-person gondolas traveling 160 feet?above the ground are undoubtedly more appealing.?
TfL says the system will move 2,000 passengers an hour -- the equivalent capacity of more than 30 buses.
More Olympic coverage from msnbc.com and NBC News:
NEW YORK (AP) ? Facebook updated its status to "public company" on Friday.
After an anxiety-filled half-hour delay, its stock began trading on the Nasdaq Stock Market for the first time as investors were finally able to put a dollar value on the company that turned online social networking into a global cultural phenomenon.
By early afternoon, the stock was trading at around $41, an 8 percent increase for the day. That means Facebook is worth about $112 billion, more than Amazon.com, McDonalds and storied Silicon Valley icons Hewlett-Packard and Cisco.
But as many people looked for a big first-day pop in Facebook's share price, the single-digit increase was somewhat of a letdown.
"It wasn't quite as exciting as it could have been," said Nick Einhorn, an analyst with IPO advisory firm Renaissance Capital. "But I don't think we should view it as a failure."
Indeed, the small jump in price could be seen as an indication that Facebook and the investment banks that arranged the initial public offering priced the stock in an appropriate range.
It's also a supply and demand issue. Facebook offered nearly 20 percent of its available stock in the IPO, so there was enough to meet demand. In comparison, Google offered just 7.2 percent of its stock when it went public in 2004.
To IPOdesktop's Francis Gaskins, it means mom-and-pop investors are becoming "much more educated and careful" about not buying into hype. And he said that the banks taking Facebook public have learned from the 10 IPOs of social media companies in the past year and are better able to gauge how much stock to make available in an initial offering. He said a rise of 5 percent to 8 percent in this "tough market" is a success.
It might not have been possible for the social network to live up to the hype that led up to its IPO. It's Facebook, after all, a place where people are emotionally invested in endless online diversions and rekindled friendships, an endless depository of baby photos, favorite songs and fleeting memories.
"It's probably one of the first times there has been an IPO where everyone sort of has a stake in the outcome," said Gartner analyst Brian Blau. While most Facebook users won't see a penny from the offering, they are all intimately familiar with the company.
Earlier Friday, the company's 28-year-old CEO, Mark Zuckerberg, smiled as he rang the opening bell from Facebook's headquarters in Menlo Park, Calif. Surrounded by cheering Facebook employees and wearing his signature hoodie, he pushed the button that signals the opening of the stock market in New York. The morning's events followed an all-night "hackathon" at the company, where engineers stayed up coding software and conjuring up new ideas for Facebook and its 900 million users.
"Right now this all seems like a big deal. Going public is an important milestone in our history. But here's the thing, our mission isn't to be a public company. Our mission is to make the world more open and connected," Zuckerberg said. "In the past eight years, all of you out there have built the largest community in the history of the world. You've done amazing things that we never would have dreamed of and I can't wait to see what you guys all do going forward."
Afterward, employees tried to get back to business as usual, building the company under immense new pressure to meet shareholders' expectations. To remind everyone not to get caught up in the hoopla, Facebook's 2,000 employees were given t-shirts that read "Stay focused & keep hacking."
On Thursday, Facebook and the investment bankers settled on a price of $38 per share. The company and its early investors raised $16 billion in the offering, which valued Facebook at $104 billion. That makes Facebook the most valuable U.S. company to ever go public.
Now, the stock market will assign a dollar value to Facebook that will rise and fall with investor whims. It will be subject to broad economic forces and held accountable for profit it earns ?or loses? from one quarter to the next.
But Facebook is one a rare companies whose IPO transcends Wall Street's money lust. It is a cultural touchstone for the way technology reshapes our lives. Since its start as a scrappy network for college students, Facebook has come to define social networking by getting people around the world to share everything from photos of their pets to their deepest thoughts.
It has done so while becoming one of the few profitable Internet companies to go public recently. It had net income of $205 million in the first three months of 2012, on revenue of $1.06 billion. In all of 2011, it earned $1 billion, up from $606 million a year earlier. That's a far cry from 2007, when it posted a net loss of $138 million and revenue of $153 million. The company makes most of its money from advertising. It also takes a cut from the money people spend on virtual items in Facebook games such as "FarmVille."
Facebook's public debut marks a new milestone in the history of the Internet. In 1995, Netscape Communications' IPO gave people their first chance to invest in a company whose graphical Web browser made the Internet more engaging and easier to navigate. Its hotly anticipated IPO lit the fuse that ignited the dot-com boom. That explosion of entrepreneurial activity and investment culminated five years later in a devastating bust that obliterated the notion that the Internet had hatched a "new economy".
It took Google Inc.'s IPO in 2004 to prove that an Internet company with a disruptive idea could be profitable. In the process, the Internet search leader is forcing other industries to adapt to a new order where people have come to expect to be able to find just about anything they want by entering a few words into a box on any device with an Internet connection.
Facebook's IPO heralds a new phase of the Internet's evolution. This social era makes connections among people as important as Google's massive index of Web links. Still, the IPO will raise new pressures for Facebook to generate more revenue, perhaps by digging further into the trove of revealing information that people share on the network to sell even more targeted ads.
Facebook's IPO almost certainly will enrich other up-and-coming entrepreneurs as Zuckerberg uses the company's cash and stock to buy other startups in an effort to being in other talented engineers and promising technology. That's what has been doing for years. Since it went public in 2004, Google has spent $10.2 billion buying nearly 200 other companies. Those figures don't include Google's still-pending $12.5 billion acquisition of cellphone maker Motorola Mobility Holdings Inc., which is still awaiting regulatory approval in China.
Zuckerberg's biggest deal so far came when he agreed to buy Instagram, a maker of a popular mobile app for photos, for $1 billion. Because most of the deal is being paid for in stock, Instagram is already getting richer. Based on Facebook's IPO price of $38 per share, Instagram is in line to receive nearly $1.2 billion.
Though Zuckerberg rang the Nasdaq opening bell from California, people outside the stock market in Times Square snapped photos of a big blue Facebook sign that lit up the building. Some of them used their smart phones to check in to the Nasdaq on Facebook. Frederick Nolde, who was visiting from Richmond, Va., said he bought 100 shares through the online brokerage eTrade.
He thinks the company is worth $100 billion. "I think Google is a good comparison and it's worth $200 to 300 billion. The real question is how they do in mobile. If they can figure that out they'll do well."
___
AP Technology Writer Michael Liedtke in San Francisco, Associated Press Reporter Marcus Wohlsen in Menlo Park, AP Business Writers Bernard Condon and Joseph Pisani in New York contributed to this story.
Elizabeth Platz at 2012 Johns Hopkins Nano-Bio Symposium. Photo by Stephanie Fraley
?Where do cancer data even come from?? This was the question posed to Dr. Elizabeth Platz prior to the 2012 Johns Hopkins University Nano-Bio Symposium. Dr. Platz is the Martin D. Abeloff, MD Scholar in Cancer Prevention and director of the Cancer Epidemiology, Prevention, & Control Training Program at the Johns Hopkins Bloomberg School of Public Health. As a cancer epidemiologist, Platz studies the frequency, distribution, and causes of cancer using data collected by the National Cancer Institute. By looking at these data, epidemiologists hope to understand why cancer occurs and what might be done to prevent it. ?Cancer mortality in the US is declining and has been for some time,? Platz said. ?The question is why.?
Dr. Platz and other cancer epidemiologists work on answering this ?why.? Platz explained that cancer epidemiologists hypothesize why cancer rates may be high in certain segments of the population, follow a cohort of at-risk patients to see if they develop disease, and then try to figure out if some risk factor could be partially responsible for the disease. By identifying risk factors, cancer epidemiologists can influence public policy and promote preventative action.
Increasingly, cancer epidemiologists are working with researchers trying to answer basic science questions. An example of Dr. Platz?s recent interdisciplinary work involves finding tissue-based markers for prostate cancer, which could inform diagnoses and treatment decisions made by clinicians. One potential marker the researchers found is telomere length. Telomeres are repeated units on the ends of all chromosomes. Platz and her team of collaborators at Johns Hopkins showed that variability in tumor cell telomere length gave a 40-times greater risk for recurrence when compared with low telomere length variability. In the future, telomere length may be quantified following removal of a patient?s primary tumor before deciding on the next course of treatment.
Dr. Platz finished her talk by discussing the importance of having scientists in the nanobiotechnology fields work with cancer epidemiologists. Nanobiotechnology could greatly help epidemiologists measure exposure to environmental toxins and handle large amounts of data, allowing the epidemiologists to better make and test hypotheses about why cancer occurs. Future collaborations have the potential to drastically improve cancer care and patient survival rates.
Story by?Colin Paul, a Ph.D. student in the Department of Chemical and Biomolecular Engineering at Johns Hopkins with interests in microfabrication and cancer metastasis.
The ?Global Defence Survey 2012? states that 42% of ?respondents (senior defence business decision makers) expect an increase in marketing expenditure in 2012, while only 10% of respondents expect a decrease. Marketing budgets of global defence industry supplier companies are expected to rise by an average of 5.5% over the next 12 months. Supplier respondents plan to spend more on social media and different online media formats such as newsletters, blogs, videos, webcasts, podcasts, online resource centres and talkback.
Global defence industry respondents identifyIndiato be the most important region for growth among emerging markets, along withMiddle EastandBrazil. The Indian defence industry is a fast growing market in the world as a result of demand for advanced military hardware and the concerns of domestic insurgencies and hostility from neighbouring countries.?View the report
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> Construction Wood in BRIC market report available > China: Freight transport market to grow 7.1% by 2013 > Hungary: Latest risk analysis report now available > Germany: Foodservice sector set for good growth > China: Auto wheel exports worth $4,382bn in 2011
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We can learn a lot from other species Public release date: 17-May-2012 [ | E-mail | Share ]
Contact: Irene Perovsek irene.perovsek@isb-sib.ch 41-078-876-1129 Swiss Institute of Bioinformatics
A long-held assumption confirmed
Researchers at the SIB Swiss Institute of Bioinformatics and the EMBL-European Bioinformatics Institute have confirmed the long-held belief that studying the genes we share with other animals is useful. The study, published today in the open access journal PLoS Computational Biology, shows how bioinformatics makes it possible to test the fundamental principles on which life science is built.
Studying genes helps life science researchers understand how our bodies work and how diseases progress. Scientists have long looked to model species mice, for example to understand human biology. This is at the root of what is called the 'ortholog conjecture': the idea that we can take what we learn from a few species and apply it to many.
The ortholog conjecture
To get an idea of what orthologs are about, consider wolf teeth. If we want to know more about our canine teeth, would we learn more by looking at the canines of wolves? Or would it be better to look at our molars? The answer might not be straightforward. In genetics, scientists address a similar question: Is it better to compare genes in mice and humans that directly descend from a common ancestor (these are called 'orthologs') or to compare imperfect copies of genes within a human being (the 'paralogs')?
Assume nothing
For the past 40 years, scientists have gone with Plan A: the orthologs, and this has worked quite well. Studying genes in model species has provided invaluable insights in all areas of biology. But until now, there hasn't been enough data to answer this question with authority. With advances in biotechnology producing vast quantities of data every day, there is finally enough to settle the debate.
Using advanced computational techniques on data derived from tens of thousands of scientific articles, the researchers analysed 400 000 pairs of genes (orthologs and paralogs) from 13 different species. The team compared the two approaches and picked a winner.
"We have the data to prove that the study of orthologs is indeed useful, but we are only at the beginning," says Prof. Marc Robinson-Rechavi of SIB and the University of Lausanne. "This is at the heart of all of comparative genomics, in which we try to extrapolate knowledge from a handful of organisms and apply it to all of life."
"We found that current experimental annotations do support the standard model," explains Christophe Dessimoz of EMBL-EBI. "Our work corroborates the assumption that studying the genes of other species whether mice, yeast, or even bacteria can elucidate aspects of human biology."
The same question has recently been addressed by Matthew Hahn and colleagues (University of Indiana, USA), whose different conclusion sparked some debate. The new research demonstrates that these controversial results were due to overlooked biases in the collective knowledge of gene function. Controlling for these, the new study unequivocally supports the ortholog conjecture and the fact that studying species we are only distantly related to even worms, flies, yeasts or bacteria is relevant and useful.
Open science
This study was made possible by the tradition of open science in bioinformatics, which is strongly supported by SIB, EMBL-EBI and ELIXIR, the incipient infrastructure for life science data in Europe. All of the data used in the study was freely available, including the genome sequences and experimental knowledge described in thousands of publications. ELIXIR will build on this tradition and provide the next generation of infrastructure for biological information in Europe and worldwide.
###
About the study
Adrian M. Altenhoff, Romain A. Studer, Marc Robinson-Rechavi and Christophe Dessimoz. (2012) Resolving the ortholog conjecture: orthologs tend to be weakly, but significantly, more similar in function than paralogs. PLoS Comp Biol (in press). DOI: 10.1371/journal.pcbi.1002514
SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation recognized of public utility. It federates bioinformatics activities throughout Switzerland. Its two-fold mission is to provide world-class core bioinformatics resources to the national and international life science research community in key fields such as genomics, proteomics and systems biology; as well as to lead and coordinate the field of bioinformatics in Switzerland. It has a long-standing tradition of producing state-of-the-art software for the life science research community, as well as carefully annotated databases. SIB includes 31 world-class research and service groups, which gather more than 480 researchers, in the fields of proteomics, transcriptomics, genomics, systems biology, structural bioinformatics, evolutionary bioinformatics, modelling, imaging, biophysics, and population genetics in Basel, Bern, Fribourg, Geneva, Lausanne, and Zurich. SIB's expertise is widely appreciated and its services are used by life sciences researchers worldwide.
www.isb-sib.ch
About EMBL-EBI
The European Bioinformatics Institute (EBI) is part of the European Molecular Biology Laboratory (EMBL) and is located on the Wellcome Trust Genome Campus in Hinxton near Cambridge, UK. The EBI grew out of EMBL's pioneering work in providing public biological databases to the research community. It hosts some of the world's most important collections of biological data, including DNA sequences (ENA), protein sequences (UniProt), animal genomes (Ensembl), 3D structures (the Protein Databank in Europe), data from gene expression experiments (ArrayExpress), protein-protein interactions (IntAct) and pathway information (Reactome). EMBL-EBI hosts several research groups and its scientists continually develop new tools for the biocomputing community. www.ebi.ac.uk
About EMBL
The European Molecular Biology Laboratory is a basic research institute funded by public research monies from 20 member states (Austria, Belgium, Croatia, Denmark, Finland, France, Germany, Greece, Iceland, Ireland, Israel, Italy, Luxembourg, the Netherlands, Norway, Portugal, Spain, Sweden, Switzerland and the United Kingdom) and associate member state Australia. Research at EMBL is conducted by approximately 85 independent groups covering the spectrum of molecular biology. The Laboratory has five units: the main Laboratory in Heidelberg, and outstations in Grenoble, Hamburg, Hinxton and Monterotondo (near Rome). The cornerstones of EMBL's mission are: to perform basic research in molecular biology; to train scientists, students and visitors at all levels; to offer vital services to scientists in the member states; to develop new instruments and methods in the life sciences and to actively engage in technology transfer activities. Around 190 students are enrolled in EMBL's International PhD programme. Additionally, the Laboratory offers a platform for dialogue with the general public through science communication activities such as lecture series, visitor programmes and the dissemination of scientific achievements. www.embl.org
Contacts:
Irne Perovsek,
Head of Communications SIB Swiss Institute of Bioinformatics
Quartier Sorge - Btiment Gnopode, 1015 Lausanne
+41 21 692 40 54 / +41 (0)78 876 11 29
E-mail: irene.perovsek@isb-sib.ch
Mary Todd-Bergman,
Press Officer EMBL-European Bioinformatics Institute
Hinxton, UK
+44 1223 494 665
E-mail: contactpress@ebi.ac.uk
Web: www.ebi.ac.uk/information/news
Katrina Pavelin
Press Officer EMBL-European Bioinformatics Institute
Hinxton, UK
+44 1223 494 452
E-mail: contactpress@ebi.ac.uk
Web: www.ebi.ac.uk/information/news
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
We can learn a lot from other species Public release date: 17-May-2012 [ | E-mail | Share ]
Contact: Irene Perovsek irene.perovsek@isb-sib.ch 41-078-876-1129 Swiss Institute of Bioinformatics
A long-held assumption confirmed
Researchers at the SIB Swiss Institute of Bioinformatics and the EMBL-European Bioinformatics Institute have confirmed the long-held belief that studying the genes we share with other animals is useful. The study, published today in the open access journal PLoS Computational Biology, shows how bioinformatics makes it possible to test the fundamental principles on which life science is built.
Studying genes helps life science researchers understand how our bodies work and how diseases progress. Scientists have long looked to model species mice, for example to understand human biology. This is at the root of what is called the 'ortholog conjecture': the idea that we can take what we learn from a few species and apply it to many.
The ortholog conjecture
To get an idea of what orthologs are about, consider wolf teeth. If we want to know more about our canine teeth, would we learn more by looking at the canines of wolves? Or would it be better to look at our molars? The answer might not be straightforward. In genetics, scientists address a similar question: Is it better to compare genes in mice and humans that directly descend from a common ancestor (these are called 'orthologs') or to compare imperfect copies of genes within a human being (the 'paralogs')?
Assume nothing
For the past 40 years, scientists have gone with Plan A: the orthologs, and this has worked quite well. Studying genes in model species has provided invaluable insights in all areas of biology. But until now, there hasn't been enough data to answer this question with authority. With advances in biotechnology producing vast quantities of data every day, there is finally enough to settle the debate.
Using advanced computational techniques on data derived from tens of thousands of scientific articles, the researchers analysed 400 000 pairs of genes (orthologs and paralogs) from 13 different species. The team compared the two approaches and picked a winner.
"We have the data to prove that the study of orthologs is indeed useful, but we are only at the beginning," says Prof. Marc Robinson-Rechavi of SIB and the University of Lausanne. "This is at the heart of all of comparative genomics, in which we try to extrapolate knowledge from a handful of organisms and apply it to all of life."
"We found that current experimental annotations do support the standard model," explains Christophe Dessimoz of EMBL-EBI. "Our work corroborates the assumption that studying the genes of other species whether mice, yeast, or even bacteria can elucidate aspects of human biology."
The same question has recently been addressed by Matthew Hahn and colleagues (University of Indiana, USA), whose different conclusion sparked some debate. The new research demonstrates that these controversial results were due to overlooked biases in the collective knowledge of gene function. Controlling for these, the new study unequivocally supports the ortholog conjecture and the fact that studying species we are only distantly related to even worms, flies, yeasts or bacteria is relevant and useful.
Open science
This study was made possible by the tradition of open science in bioinformatics, which is strongly supported by SIB, EMBL-EBI and ELIXIR, the incipient infrastructure for life science data in Europe. All of the data used in the study was freely available, including the genome sequences and experimental knowledge described in thousands of publications. ELIXIR will build on this tradition and provide the next generation of infrastructure for biological information in Europe and worldwide.
###
About the study
Adrian M. Altenhoff, Romain A. Studer, Marc Robinson-Rechavi and Christophe Dessimoz. (2012) Resolving the ortholog conjecture: orthologs tend to be weakly, but significantly, more similar in function than paralogs. PLoS Comp Biol (in press). DOI: 10.1371/journal.pcbi.1002514
SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation recognized of public utility. It federates bioinformatics activities throughout Switzerland. Its two-fold mission is to provide world-class core bioinformatics resources to the national and international life science research community in key fields such as genomics, proteomics and systems biology; as well as to lead and coordinate the field of bioinformatics in Switzerland. It has a long-standing tradition of producing state-of-the-art software for the life science research community, as well as carefully annotated databases. SIB includes 31 world-class research and service groups, which gather more than 480 researchers, in the fields of proteomics, transcriptomics, genomics, systems biology, structural bioinformatics, evolutionary bioinformatics, modelling, imaging, biophysics, and population genetics in Basel, Bern, Fribourg, Geneva, Lausanne, and Zurich. SIB's expertise is widely appreciated and its services are used by life sciences researchers worldwide.
www.isb-sib.ch
About EMBL-EBI
The European Bioinformatics Institute (EBI) is part of the European Molecular Biology Laboratory (EMBL) and is located on the Wellcome Trust Genome Campus in Hinxton near Cambridge, UK. The EBI grew out of EMBL's pioneering work in providing public biological databases to the research community. It hosts some of the world's most important collections of biological data, including DNA sequences (ENA), protein sequences (UniProt), animal genomes (Ensembl), 3D structures (the Protein Databank in Europe), data from gene expression experiments (ArrayExpress), protein-protein interactions (IntAct) and pathway information (Reactome). EMBL-EBI hosts several research groups and its scientists continually develop new tools for the biocomputing community. www.ebi.ac.uk
About EMBL
The European Molecular Biology Laboratory is a basic research institute funded by public research monies from 20 member states (Austria, Belgium, Croatia, Denmark, Finland, France, Germany, Greece, Iceland, Ireland, Israel, Italy, Luxembourg, the Netherlands, Norway, Portugal, Spain, Sweden, Switzerland and the United Kingdom) and associate member state Australia. Research at EMBL is conducted by approximately 85 independent groups covering the spectrum of molecular biology. The Laboratory has five units: the main Laboratory in Heidelberg, and outstations in Grenoble, Hamburg, Hinxton and Monterotondo (near Rome). The cornerstones of EMBL's mission are: to perform basic research in molecular biology; to train scientists, students and visitors at all levels; to offer vital services to scientists in the member states; to develop new instruments and methods in the life sciences and to actively engage in technology transfer activities. Around 190 students are enrolled in EMBL's International PhD programme. Additionally, the Laboratory offers a platform for dialogue with the general public through science communication activities such as lecture series, visitor programmes and the dissemination of scientific achievements. www.embl.org
Contacts:
Irne Perovsek,
Head of Communications SIB Swiss Institute of Bioinformatics
Quartier Sorge - Btiment Gnopode, 1015 Lausanne
+41 21 692 40 54 / +41 (0)78 876 11 29
E-mail: irene.perovsek@isb-sib.ch
Mary Todd-Bergman,
Press Officer EMBL-European Bioinformatics Institute
Hinxton, UK
+44 1223 494 665
E-mail: contactpress@ebi.ac.uk
Web: www.ebi.ac.uk/information/news
Katrina Pavelin
Press Officer EMBL-European Bioinformatics Institute
Hinxton, UK
+44 1223 494 452
E-mail: contactpress@ebi.ac.uk
Web: www.ebi.ac.uk/information/news
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Contact: Heather Houlton hrh@agiweb.org American Geological Institute
Alexandria, VA In continuation of the Geoscience Academic Provenance research series conducted by Houlton (Geoscience Currents 45-48, and 57-58), Geoscience Currents 59 presents quantitative data collected from participants through a Likert-based survey. Participants were asked to rate their feelings toward geoscience on a scale from 1 to 7. The aggregated responses illuminated the changes over time in the students' attitudes toward pursuing geoscience.
A copy of Geoscience Currents 59 can be found online and downloaded from http://www.agiweb.org/workforce/currents.html.
Geoscience Currents are quick snapshots of data released by AGI on the status of the geoscience workforce. The Currents also represent data collaborations with other societies, employers, and professionals. Topics for these reports are inspired by inquiries from geoscience community leaders. Interested in participating in AGI's Geoscience Currents? Visit http://www.agiweb.org/workforce/currents.html, and register to receive free email updates containing all the new Geoscience Currents.
###
The American Geosciences Institute is a nonprofit federation of geoscientific and professional associations that represents more than 250,000 geologists, geophysicists and other earth scientists. Founded in 1948, AGI provides information services to geoscientists, serves as a voice of shared interests in the profession, plays a major role in strengthening geoscience education, and strives to increase public awareness of the vital role the geosciences play in society's use of resources, resiliency to natural hazards, and interaction with the environment.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Contact: Heather Houlton hrh@agiweb.org American Geological Institute
Alexandria, VA In continuation of the Geoscience Academic Provenance research series conducted by Houlton (Geoscience Currents 45-48, and 57-58), Geoscience Currents 59 presents quantitative data collected from participants through a Likert-based survey. Participants were asked to rate their feelings toward geoscience on a scale from 1 to 7. The aggregated responses illuminated the changes over time in the students' attitudes toward pursuing geoscience.
A copy of Geoscience Currents 59 can be found online and downloaded from http://www.agiweb.org/workforce/currents.html.
Geoscience Currents are quick snapshots of data released by AGI on the status of the geoscience workforce. The Currents also represent data collaborations with other societies, employers, and professionals. Topics for these reports are inspired by inquiries from geoscience community leaders. Interested in participating in AGI's Geoscience Currents? Visit http://www.agiweb.org/workforce/currents.html, and register to receive free email updates containing all the new Geoscience Currents.
###
The American Geosciences Institute is a nonprofit federation of geoscientific and professional associations that represents more than 250,000 geologists, geophysicists and other earth scientists. Founded in 1948, AGI provides information services to geoscientists, serves as a voice of shared interests in the profession, plays a major role in strengthening geoscience education, and strives to increase public awareness of the vital role the geosciences play in society's use of resources, resiliency to natural hazards, and interaction with the environment.
[ | E-mail | Share ]
?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Former Bosnian Serb military commander Gen. Ratko Mladic, right, and a UN security guard, left, are seen at the start of his trial at the Yugoslav war crimes tribunal in The Hague, Netherlands, Wednesday May 16, 2012. Twenty years after the opening shots of the Bosnian War, Mladic has gone on trial on charges of genocide, crimes against humanity and war crimes, his appearance at the UN tribunal marks the end of a long wait for justice to survivors of the 1992-95 war that left some 100,000 people dead. (AP Photo/Toussaint Kluiters, Pool)
Former Bosnian Serb military commander Gen. Ratko Mladic, right, and a UN security guard, left, are seen at the start of his trial at the Yugoslav war crimes tribunal in The Hague, Netherlands, Wednesday May 16, 2012. Twenty years after the opening shots of the Bosnian War, Mladic has gone on trial on charges of genocide, crimes against humanity and war crimes, his appearance at the UN tribunal marks the end of a long wait for justice to survivors of the 1992-95 war that left some 100,000 people dead. (AP Photo/Toussaint Kluiters, Pool)
Former Bosnian Serb military commander Gen. Ratko Mladic, center rear, a UN security guard, rear right, and member of his defense, front, are seen at the start of his trial at the Yugoslav war crimes tribunal in The Hague, Netherlands, Wednesday May 16, 2012. Twenty years after the opening shots of the Bosnian War, Mladic has gone on trial on charges of genocide, crimes against humanity and war crimes, his appearance at the UN tribunal marks the end of a long wait for justice to survivors of the 1992-95 war that left some 100,000 people dead. (AP Photo/Toussaint Kluiters, Pool)
Former Bosnian Serb military commander Gen. Ratko Mladic is seen at the start of his trial at the Yugoslav war crimes tribunal in The Hague, Netherlands, Wednesday May 16, 2012. Twenty years after the opening shots of the Bosnian War, Mladic has gone on trial on charges of genocide, crimes against humanity and war crimes, his appearance at the UN tribunal marks the end of a long wait for justice to survivors of the 1992-95 war that left some 100,000 people dead. (AP Photo/Toussaint Kluiters, Pool)
Former Bosnian Serb military commander Gen. Ratko Mladic is seen at the start of his trial at the Yugoslav war crimes tribunal in The Hague, Netherlands, Wednesday May 16, 2012. Twenty years after the opening shots of the Bosnian War, Mladic has gone on trial on charges of genocide, crimes against humanity and war crimes, his appearance at the UN tribunal marks the end of a long wait for justice to survivors of the 1992-95 war that left some 100,000 people dead. (AP Photo/Toussaint Kluiters, Pool)
Former Bosnian Serb military commander Gen. Ratko Mladic is seen at the start of his trial at the Yugoslav war crimes tribunal in The Hague, Netherlands, Wednesday May 16, 2012. Twenty years after the opening shots of the Bosnian War, Mladic has gone on trial on charges of genocide, crimes against humanity and war crimes, his appearance at the UN tribunal marks the end of a long wait for justice to survivors of the 1992-95 war that left some 100,000 people dead. (AP Photo/Toussaint Kluiters, Pool)
THE HAGUE, Netherlands (AP) ? Twenty years after the opening shots of the Bosnian War, former Bosnian Serb military commander Gen. Ratko Mladic went on trial Wednesday at a U.N. tribunal on 11 charges of genocide, crimes against humanity and war crimes.
The ailing 70-year-old Mladic's appearance at the Yugoslav war crimes tribunal marks the end of a long wait for justice to survivors of the 1992-95 war that left some 100,000 people dead. The trial is also a landmark for the U.N. court and international justice ? Mladic is the last suspect from the Bosnian war to go on trial here.
Mladic, wearing a suit and tie, gave a thumbs-up and clapped to supporters in the court's public gallery as the trial got under way Wednesday. He occasionally wrote notes and showed no emotion as prosecutors began outlining his alleged crimes.
Munira Subasic, who lost 22 family members in the 1995 Srebrenica massacre, was among a group of relatives of war dead heading into the courtroom to face Mladic.
The 65-year-old said she wanted to look him in the eye "and ask him if he will repent for what he did."
Presiding Judge Alphons Orie of the Netherlands said at the outset that the court was considering postponing the presentation of evidence, due to start May 29, due to "errors" by prosecutors in disclosing evidence to the defense. Prosecutor Dermot Groome said he would not oppose a "reasonable adjournment."
Groome began his opening statement by focusing on the plight of a 14-year-old boy whose father and uncle were among 150 men murdered by Bosnian Serb forces in November 1992.
He said Mladic's forces continued such killings through to 1995, when they massacred some 8,000 Muslim men in the Srebrenica enclave, the worst mass murder in Europe since World War II.
"By the time Mladic and his troops murdered thousands in Srebrenica ... they were well-rehearsed in the craft of murder," Groome told the court.
He then showed judges video of the aftermath of a notorious shelling of a market in Markale, in the Bosnian capital Sarajevo, that killed dozens of people.
He said all the attacks were part of an "overarching" plan to ethnically cleanse parts of Bosnia of non-Serbs.
Prosecutors will show evidence "beyond reasonable doubt the hand of Mr. Mladic in each of these crimes," Groome said.
Mladic has refused to enter pleas, but he denies wrongdoing, saying he acted to defend Serbs in Bosnia. If he is convicted, he faces a maximum sentence of life imprisonment.
He suffered a stroke while in hiding and has had other health problems since arriving in The Hague. He now looks little like the burly, swaggering general who marshaled his troops as the world watched during the Bosnian war.
His trial opened as the case against his former political master, Radovan Karadzic, has reached its halfway stage at the same court. Both men face virtually identical 11-count indictments alleging they masterminded the ethnic cleansing of Bosnia.
Karadzic and Mladic were indicted together 17 years ago, but their cases were split when Karadzic was captured in Serbia in 2008 and transferred to The Hague. It was another three years before Mladic was finally arrested in a village near Belgrade, ending 15 years as one of the world's most-wanted fugitives.
Izudin Alic, a Muslim boy made famous in 1995 by images of Mladic patting his face and handing him chocolate, said he wants swift justice after waiting for so long. He planned to watch the opening of the trial on television.
"Just like everyone else, I want him to be tried and sentenced as fast as possible. I hope that the trial will not drag on," he said as he visited his father's grave in Potocari, near Srebrenica. "I want him to be sentenced as soon as possible."
____
Sabina Niksic in Srebrenica contributed to this report.
If you were watching Samsung's May 3 presentation closely enough, you might have seen this before -- it's Samsung's (slightly odd, if we're honest) TV spot for the upcoming Galaxy S III, which the manufacturer's uploaded separately for the first time today. In amongst clips of happy, attractive people jumping around and enjoying their phones, you'll spot a series of broad slogans alluding to some of the major functions of the phone. Apparently the Galaxy S III is the phone that "keeps track of your loved ones," "recognizes who you are," "follows your every move," and "waits until you're asleep."
Sleep tight. We've got the video itself embedded after the break.
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Public release date: 17-May-2012
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